Fluorometric determination of ornidazole by using BSA coated copper nanoclusters as a novel turn off sensor

A fluorescent probe based on bovine serum albumin stabilized copper nanoclusters (BSA-CuNCs) was developed for the selective and sensitive determination of ornidazole (ORN). The were synthesized via a one-pot hydrothermal process in basic media. characterized BSA-CuNCs have less than 3 nm particle size exhibited blue emission at 405 when excited 325 nm. Synthesized successfully applied as turn-off ORN pharmaceutical dosage forms. quenching mechanism created an inner filter effect (IFE). method linear concentration range 0.52-13.56 μg mL-1 with low limit detection (LOD) 0.01 mL-1. High recovery values (98.5%-102.42%) RSD% (0.25%-2.73%) obtained. can be used their selective, simple, rapid, inexpensive properties.